If you’re researching skin boosters, you’ve probably seen two names come up again and again: Profhilo and Polynucleotides. At my Birmingham skin clinic, women often ask: “What’s the difference — and which one is better for me?” Let’s break it down simply so you can make the right choice for your skin.
What is Profhilo?
Profhilo is an injectable treatment made from pure hyaluronic acid. Unlike filler, it doesn’t add volume — instead, it spreads under the skin to deeply hydrate and stimulate collagen and elastin. Clients love it for:
- Boosting hydration
- Softening fine lines
- Giving skin a plumper, fresher look
Results last around 6 months and work best with 2 sessions, 4 weeks apart.
What are Polynucleotides?
Polynucleotides are the new generation of skin regeneration. They’re made from DNA fragments that reprogram your skin cells to repair and heal. Think of it as training your skin to behave younger. They help with:
- Improving elasticity and firmness
- Reducing pigmentation and inflammation
- Brightening dark circles
- Long-term skin health and repair
Results build over a course and improve with time, not just a quick “boost.”
| Feature | Profhilo | Polynucleotides |
|---|---|---|
| Main Benefit | Deep hydration + collagen boost | Regeneration, repair & healing |
| Best For | Dehydrated, crepey skin | Loss of elasticity, pigmentation, dark circles |
| Treatment Plan | 2 sessions, 4 weeks apart | Usually 3–4 sessions, spaced apart |
| Results | Instant plumpness, smoother skin | Ongoing improvement, long-term repair |
| Longevity | ~6 months | Builds gradually, can last longer with maintenance |
Which treatment is best for you?
- If your main concern is dry, crepey, tired-looking skin, Profhilo is a great choice.
- If you want to restore skin health, repair damage, and tackle deeper issues like pigmentation or dark circles, polynucleotides are the stronger option.
Many of my Birmingham clients actually choose to combine both treatments for maximum hydration and regeneration.
Final note:
Both treatments are incredible, but the best choice depends on your skin goals. During your consultation at Sorelle Aesthetics, we’ll look at your skin in detail and decide whether Profhilo, Polynucleotides, or a combination will give you the results you’re looking for.
